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API production and quality assurance interview questions

ROLL COMPACTOR

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January 17, 2020

ROLL COMPACTOR :
The features of roll compactor are it will improve the bulk density to achieve better granulation of sieve analysis improve product quality and reduce the process cost.

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THEORITICAL YIELD VS ACTUAL YIELD

June 20, 2020

THEORITICAL YIELD VS ACTUAL YIELD : Amounts of products calculated from the complete reaction of the limiting reagent are called theoretical yields , whereas the amount actually produced of a product is the actual yield . The ratio of actual yield to theoretical yield expressed in percentage is called the percentage yield

REACTOR OPERATION

December 20, 2019

1. REACTOR Types of reactor :ssr,glr,hastolly reactor Types of condensers :sheel and tube Types of jackets: shell and limpet type Moc: ss316,ss316 contains 16-18%chromium and 11-14% nickel and remaining iron. ss reactor suitable for pH 7.0 to 14 and glr suitable for pH 1.0 to 7.0 Types of agitator s:anchor,propeller,turbine Baffles: paddle type baffles,using onside and two opposite sides in reactor Reactor capacity and part : as per batch size and urs 1.motor 2.gear box 3.agitator 4.bottom value 5.jacket 6.temperature sensor 7.safety value 8.nitrogen line 9.manhole or hand hole 10.flame arrester 11. reflux line Guages: 1.pressure guage: Measured the unit of forcesurface area.pressure is measured in kg/cm2 or lb/cm2 2.vacuum guage :A vacuum is a space in which the pressure of a gas is low compared to the atmospheric pressure. The measure of vacuum is associated with pressure. Vacuum gauges and instruments are used in conjunction with vacuum senso...

pharmaceutical warehouse process

March 25, 2020

1. What is the role of Warehouse in Pharmaceuticals : Warehouse in pharmaceutical plays an important role which includes Receiving of Raw material, Packing material, Finished products, Storage of materials in required storage condition (Temperature and RH), Dispensing of Raw and Packing materials which are required for manufacturing of the batches , Dispatch of Finished (the products which completed all stages i.e. manufacturing and Final packing) products. 2. What is Good Warehouse Practices (GWP): Good Warehouse Practices (GWP) includes Entry and Exit to warehouse with proper gowning, Receiving and storage of materials in required storage condition, Proper Labeling of Raw and packing materials, Systematic arrangement of materials in warehouse, Use of required personnel protective equipment during dispensing of materials, Storage of controlled drug substances, Training of persons working in warehouse, Verification of Incoming materials with respect to Quantity and...